National Research Institute Careers

Current Job Openings

Develop your clinical research career at National Research Institute. We have a team of clinical research professionals dedicated to providing healthcare advancements through clinical trials.

Sub-Investigator – Gardena

Job Summary:
The Sub-Investigator (SI) provides care to all study patients within the standards set by Principal Investigator (PI), NRI and Sponsor. This position reports to the Medical Director or Principal Investigator.
NRI’s Sub-Investigators function within the scope of their required license, as well as, follow State Laws and Federal Regulations pertaining to the conduct of clinical trials and Good Clinical Practices.

Job Duties:

  • Supporting the investigational plan (the protocol), and applicable regulations; medical and safety back-up to PI
  • Assisting PI in the training of study team members on study design, objectives, study drug, study indication, and appropriate selection of study participants, assuring adequate safeguards for study participants and strict adherence to the study protocol
  • Reviewing potential study participant’s medical history and performing physical examinations and/or any other required procedures as specified by the protocol
  • Diagnosing and/or excluding medical/psychiatric conditions for purposes of study participation as delegated
  • Obtaining informed consent from potential study participants and documenting that process according to NRI’s guidelines
  • Interpreting medical/diagnostic test results to determine eligibility of potential study participants and accessing consulting physicians if needed for test result interpretation
  • Determining appropriate tapering and titration schedules for studies that require such procedures
  • Reviewing pertinent medical records requested for study participants
  • Reviewing all laboratory reports including screening reports and reports obtained per study protocol and determining the clinical significance of abnormal test results and further appropriate evaluation
  • Consulting with potential study participants’ personal physicians concerning their participation in clinical trials and clarifying medical issues before potential study participant randomization when appropriate
  • Assessing adverse events and reviewing concomitant medications at each study visit, unscheduled study visits, and as needed at any other point during trial participation
  • Determining the clinical significance of adverse events including abnormal lab results and ECGs, and assessing their relationship to study medication
  • Making clinical determination of study participant’s ability to continue in a trial based upon study participants’ wishes, adverse events, lab tests, ECG results, concomitant medications, and efficacy of study medication
  • Consulting with PI and/or Sponsor contacts concerning study participant safety issues, Inclusion/Exclusion criteria for study participation, serious adverse events, and other participant issues


  • Maintaining and updating knowledge of NRI’s Standard Operating Procedures(SOPs) and their proper application
  • Attending investigator start-up and site initiation meetings before study enrollment
  • Participating in study related trainings as delegated
  • Assisting the Study team with training as needed
  • Being available for questions, discussions about patients and general study status, including study wide enrollment numbers, recruitment issues, and projected enrollment end dates when requested
  • Supporting study feasibility for all potential studies with attention to the ability to successfully enroll and conduct the trial
  • All other duties as assigned.
  • Clinical Research Coordinator – Huntington Park

    Job Summary:
    The CRC role contributes to the overall management and implementation of assigned research protocol. The CRC position is a key study team member working together with the Principal Investigator (PI) and other study team members to perform study specific procedures and visits. The CRC reports to the Project Manager (PM).

    Job Duties:

  • Carefully read, review and understand assigned research protocols
  • Participate in Investigators’ Meetings, web conferences and site selection meetings as requested
  • Complete all study related training as required per protocol
  • Practice good documentation practices per NRI’s SOPs and Good Clinical Practice guidelines
  • Carry out protocol procedures and clinic duties as delegated by and under the direct supervision of the Principal Investigator (PI)
  • Assist with the training of new Clinical Research Coordinators when requested
  • Ensure proper completion of source documentation at the time procedures are conducted
  • Assist the study team with corrections during CRA monitoring visit
  • Prepare for and participate in Quality Assurance (QA) and Food and Drug Administration (FDA) audits as needed
  • Support patient recruitment efforts and screening of new patients
  • Carefully assess and report any signs and symptoms of possible AEs/SAEs for study volunteers
  • Assist in patient education, counseling and reinforcement of study requirements when needed
  • Follow all NRI SOPs, Good Clinical Practice and FDA guidelines
  • Dispense study medication as authorized by and under the direction of the PI
  • Maintain Study Enrollment Logs as needed
  • Work closely with Regulatory staff in maintaining the study Regulatory binders
  • Ensure study and patient confidentiality is maintained at all times by following NRI’s SOPs and applicable HIPAA guidelines
  • Help to support a safe work place environment by observing the appropriate safety and occupational health rules and regulations
  • Ensure that the proper Informed Consent process is followed per NRI’s SOPs
  • Assist the PI and PMs with collecting lab results for PI review and follow-up care if needed
  • Other duties as assigned
  • Outpatient Clinic Coordinator – Santa Ana

    Job Summary:
    This position will conduct clinical intake services for all outpatient clinic visits for patients not currently enrolled in a research study under the direction of a qualified healthcare provider (HCP). Must have the ability to analyze information provided by the potential participant to determine study participation eligibility.

    Job Duties:

  • Conduct outpatient visits for new and ongoing patients not currently in a research study
  • Provide patient education and treatment options in the outpatient clinic as directed by Principal Investigator and/or medical providers
  • Responsible for the maintaining and growing our research database, including updating medical histories, updating the database with participant data, maintaining patient status, and ensuring all current outpatient clinic data is entered in NRI’s patient database by the end of each business day
  • Identify possible study participants for currently enrolling and upcoming research studies by reviewing patient charts prior to study start and maintaining updated potential study participant lists
  • Review potential study participants with Project Managers, Site Director and/or Principal Investigator/Sub-Investigator
  • Recruit subjects/patients: Speak to potential participants face to face and on the phone to identify their fit with current studies and answer any questions they may have using the screen sheet process
  • Contact patients from a variety of sources including, but not limited to, previous study patients, database entries, health fairs, advertising, brochures, personal referrals
  • Schedule appointments for qualified patients
  • Track the number of patients contracted for in each study and ensure that subject enrollment is met or exceeded according to contract and within sponsor-provided timelines
  • Create spreadsheets for sponsor to justify recruitment efforts internally
  • Provide medication to patients under supervision of the attending physician” and/or sub-investigators.
  • Order medications for the clinic
  • Obtain vitals sign including BPs, respiratory rate and pulse from patients, when needed
  • Obtain blood samples from patients, when needed
  • Process pharmacokinetic/pharmacodynamic samples according to instructions provided, when needed
  • Maintain required IATA, “Shared Care” Blood pressure certification as necessary
  • Maintain Bloodborne Pathogen Exposure Control Program
  • Maintain required CPR certification
  • Handle Hazardous waste
  • Ability to work independently
  • Other duties as assigned
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